Total Synthesis of Geranyl-Resorcinols Isolated from Mushrooms of Genus Hericium

Abstract This Short Review covers the total synthesis of tetraketide-based meroterpenoids, i.e. geranyl-resorcinols, isolated from mushrooms genus Hericium. Some these compounds are believed to be involved in unique health-promoting effects Hericium erinaceus. Herein, more than seventy natural products identified so far have been classified into seven-types based on both assumed biosynthetic pathways and chemical structures, successful syntheses summarized according structural type. 1 Introduction 2 Pioneering Synthetic Study 3 Total Synthesis Geranyl-Resorcinol with a Geranyl Side Chain (Types 1, 3, 6) 4 an Oxidized Geranyl-Derived 2, 4, 7) 5 Conclusion